2016 Publications

See below the list of our 2016 publications.
Publications 2016
  • Adam S, Dabin J, Chevallier O, Leroy O, Baldeyron C, Corpet A, Lomonte P, Renaud O, Almouzni G and Polo SE (2016) Real-time tracking of parental histones reveals their contribution to chromatin integrity following DNA damage. Mol Cell. 64(1):65-78. doi: 10.1016/j.molcel.2016.08.019.
  • Ancelin K, Syx L, Borensztein M, Ranisavljevic N, Vassilev I, Briseño-Roa L, Liu T, Metzger E, Servant N, Barillot E, Chen CJ, Schüle R and Heard E (2016) Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation. eLife 5. pii: e08851. doi: 10.7554/eLife.08851.
  • Barau J, Teissandier A, Zamudio N, Roy S, Nalesso V, Hérault Y, Guillou F and Bourc’his D* (2016) The DNA methyltransferase DNMT3C protects male germ cells from transposon activity. Science 354:909-912. doi: 10.1126/science.aah5143
  • Bohm UL, Prendergast A, Djenoune L, Nunes Figueiredo S, Gomez J, Stokes C, Kaiser S, Suster M, Kawakami K, Charpentier M, Concordet JP, Rio JP, Del Bene F, and Wyart C (2016) CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits. Nat Commun. 7:10866. doi: 10.1038/ncomms10866.
  • Bosveld F, Guirao B, Wang Z, Rivière M, Bonnet I M, Graner F and Bellaïche Y (2016) Modulation of junction tension by tumor suppressors and proto-oncogenes regulates cell-cell contacts. Development 143(4):623-34. doi: 10.1242/dev.127993.
  • Bosveld F*, Markova O, Guirao B, Martin C, Wang Z, Pierre A, Balakireva M, Gaugue I, Ainslie A, Christophorou N, Lubensky D.K, Minc N and Bellaïche Y*(2016) Epithelial tricellular junctions act as interphase cell shape sensors to orient mitosis. Nature 530(7591):495-8. doi: 10.1038/nature16970.
  • Cantone I, Bagci H, Dormann D, Dharmalingam G, Nesterova T, Brockdorff N, Rougeulle C, Vallot C, Heard E, Chaligne R, Merkenschlager M and Fisher AG (2016) Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming. Nat Commun. 7:12354. doi: 10.1038/ncomms12354.
  • Cooper S, Grijzenhout A, Underwood E, Ancelin K, Zhang T, Nesterova TB, Anil-Kirmizitas B, Bassett A, Kooistra SM, Agger K, Helin K, Heard E and Brockdorff N (2016) Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2. Nat Commun. 7:13661. doi: 10.1038/ncomms13661.
  • Coulon A and Larson DR (2016) Fluctuation Analysis: Dissecting Transcriptional Kinetics with Signal Theory. Methods Enzymol. 572:159-91. doi: 10.1016/bs.mie.2016.03.017.
  • Desponds J, Tran H, Ferraro T, Lucas T, Perez Romero C, Guillou A, Fradin C, Coppey M, Dostatni N, Walczak AM (2016) Precision of Readout at the hunchback Gene: Analyzing Short Transcription Time Traces in Living Fly Embryos. PLoS Comput Biol. 12(12):e1005256. doi: 10.1371/journal.pcbi.1005256.
  • Di Donato V, De Santis F, Auer T.O, Testa N, Sanchez-Iranzo H, Mercader N, Concordet J.P* and Del Bene F* (2016) 2C-Cas9: a versatile tool for clonal analysis of gene function. Genome Res. 26(5):681-692. doi: 10.1101/gr.196170.115.
  • Drinnenberg IA, Henikoff S and Malik HS (2016) Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus? Trends Cell Biol. 26(7):498-510. doi: 10.1016/j.tcb.2016.01.005.
  • Dunn T.W, Gebhardt C, Naumann E. A, Riegler C, Ahrens M. B, Engert F* and Del Bene F* (2016) Neural Circuits Underlying Visually Evoked Escapes in Larval Zebrafish. Neuron 89(3):613-28. doi: 10.1016/j.neuron.2015.12.021.
  • Ferraro T, Lucas T, Clémot M, De Las Heras Chanes J, Desponds J, Coppey M, Walczak AM and Dostatni N (2016) New methods to image transcription in living fly embryos: the insights so far, and the prospects. Wiley Interdiscip Rev Dev Biol. 5(3):296-310. doi: 10.1002/wdev.221.
  • Fontenas L, De Santis F, Di Donato V, Degerny C, Chambraud B, Del Bene F, and Tawk M (2016) Neuronal Ndrg4 Is Essential for Nodes of Ranvier Organization in Zebrafish. PLoS Genet. 12(11):e1006459. doi: 10.1371/journal.pgen.1006459.
  • Gauron C, Meda F, Dupont E, Albadri S, Quenech’Du N, Ipendey E, Volovitch M, Del Bene F, Joliot A, Rampon C, and Vriz S (2016) Hydrogen peroxide (H2O2) controls axon pathfinding during zebrafish development. Dev Biol 414(2):133-41. doi: 10.1016/j.ydbio.2016.05.004.
  • Giorgetti L†, Lajoie† B, Carter AC†, Attia M†, Zhan Y, Xu J, Chen CJ, Kaplan N, Chang HY, Heard E* and J Dekker* Structural organization of the inactive X chromosome. Nature 535(7613):575-9. doi: 10.1038/nature18589.
  • Guevorkian K and Maître JL (2016) Micropipette aspiration: a unique tool for exploring cell and tissue mechanics in vivo. Methods Cell Biol. 139:187-201. doi: 10.1016/bs.mcb.2016.11.012.
  • Gurard-Levin Z, Wilson L.O. Pancaldi V. Postel-Vinay S, Sousa F.G, Rayes C, Marangoni E, Gentien D, Valencia A, Pommier Y, Cottu P. and Almouzni G (2016) Chromatin regulators as a guide for cancer treatment choice. Mol Cancer Ther. 15(7):1768-77. doi: 10.1158/1535-7163.MCT-15-1008.
  • Haeussler M, Schonig K, Eckert H, Eschstruth A, Mianne J, Renaud J. B, Schneider-Maunoury S, Shkumatava A, Teboul L, Kent J, Joly JS and Concordet JP* (2016) Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR. Genome Biol. 17(1):148. doi: 10.1186/s13059-016-1012-2.
  • Maison C, Bailly D, Quivy J.P and Almouzni G (2016) The methyltransferase Suv39h1 links the SUMO pathway to HP1α marking at pericentric heterochromatin. Nat Commun. 7:12224. doi: 10.1038/ncomms12224.
  • Maison C, Quivy JP and Almouzni G (2016) Suv39h1 links the SUMO pathway to constitutive heterochromatin. Mol Cell Oncol. 3(6):e1225546, doi : 10.1080/23723556.2016.122554.
  • Maître JL, Turlier H, Illukkumbura R, Eismann B, Nédélec F and Hiiragi T (2016) Asymmetric division of contractile domains couples cell positioning and fate specification. Nature 536(7616):344-8. doi: 10.1038/nature18958.
  • Maupetit-Mehouas S, Montibus B, Nury D, Tayama C, Wassef M, Kota SK, Fogli A, Cerqueira Campos F, Hata K, Feil R, Margueron R, Nakabayashi K, Court F and Arnaud P (2016) Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive. Nucleic Acids Res. 44(2):621-35. doi: 10.1093/nar/gkv960.
  • Miné-Hattab J (2016) Lasker award 2015: Spotlight on DNA repair. Med Sci. 32(1):123-4. doi: 10.1051/medsci/20163201021.
  • Müller S and Almouzni G (2016) Chromatin dynamics during the cell cycle at centromeres. Nat Rev Genet. 18(3):192-208. doi: 10.1038/nrg.2016.157.
  • Mulugeta E, Wassenaar E, Sleddens-Linkels E, van IJcken WF, Heard E, Grootegoed JA, Just W, Gribnau J and Baarends WM (2016) Genomes of Ellobius species provide insight into the evolutionary dynamics of mammalian sex chromosomes. Genome Res. 26(9):1202-10. doi: 10.1101/gr.201665.115.
  • Nikolov I and Taddei A (2016) Linking replication stress with heterochromatin formation. Chromosoma 125(3):523-33. doi: 10.1007/s00412-015-0545-6.
  • Orsi GA, Naughtin M and Almouzni G (2016) The epigenome and cancer stem cell fate: Connected by a linker histone variant. Cell Stem Cell. 19(5):567-568. doi: 10.1016/j.stem.2016.10.010.
  • Prendergast L, Müller S, Liu Y, Huang H, Dingli F, Loew D, Vassias I, Patel D.J, Sullivan KF and Almouzni G (2016) The CENP-T/-W complex is a binding partner of the histone chaperone FACT. Genes Dev. 30(11):1313-26. doi: 10.1101/gad.275073.115.
  • Rubin T, Christophorou N and Huynh J-R (2016) How to pre-pair chromosomes for meiosis. Cell Cycle 15(5):609-10. doi: 10.1080/15384101.2015.1131524.
  • Shah RR, Cholewa-Waclaw J, Davies FC, Paton KM, Chaligne R, Heard E, Abbott CM and Bird AP (2016) Efficient and versatile CRISPR engineering of human neurons in culture to model neurological disorders. Wellcome Open Res. 1:13. doi: 10.12688/wellcomeopenres.10011.1.
  • Schoumacher M, Le Corre S, Houy A, Mulugeta E, Stern MH, Roman-Roman S and Margueron R (2016) Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status. Nat Med. 22(6):577-8. doi: 10.1038/nm.4098.
  • Subramanian VV, MacQueen AJ, Vader G, Shinohara M, Sanchez A, Borde V, Shinohara A and Hochwagen A (2016) Chromosome synapsis alleviates Mek1-dependent suppression of meiotic DNA repair. PloS Biology 14(2):e1002369. doi: 10.1371/journal.pbio.1002369.
  • Tiana G, Amitai A, Pollex T, Piolot T, Holcman D, Heard E and Giorgetti L (2016) Structural fluctuations of the chromatin fiber within topologically associating domains. Biophys J. 110(6):1234-45. doi: 10.1016/j.bpj.2016.02.003.
  • Walter M, Teissandier A, Pérez Palacios R and Bourc’his D* (2016) An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells. eLife 5. pii:e11418. doi:10.7554/eLife.11418.
  • Wassef M and Margueron R (2016) The Multiple Facets of PRC2 Alterations in Cancers. J Mol Biol. 429(13):1978-1993. doi: 10.1016/j.jmb.2016.10.012.
  • Wassef M, Michaud A and Margueron R (2016) Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors. Cell Cycle 15(17):2256-62. doi: 10.1080/15384101.2016.1208872.