2021 publications

Ray-Gallet D and Almouzni G (2021). Book chapter. The histone H3 family and its deposition pathways. In Histone mutations and cancer. Adv Exp Med Biology. vol 1283. Springer, Singapore. PMID: 33155135 https://doi.org/10.1007/978-981-15-8104-5_2 ISBN: 978-9-81-158103-8, 978-9-81-158104-5

Jeffery D, Gatto A, Podsypanina K, Charlène Renaud-Pageot, Ponce Landete R, Bonneville L, Dumont M, Fachinetti D, Almouzni G, Comm. Biology. (2021) CENP-A overexpression promotes distinct fates in human cells, depending on p53 status. DOI: 10.1038/s42003-021-01941-5

Inês Pinheiro, Maria-Elena Torres-Padilla and Genevieve Almouzni (2021) Epigenomics in the single cell era, an important read out for genome function and cell identity, Epigenomics, 13(13):981-984, Epub 2021 Jun 11. PMID: 34114476 DOI: 10.2217/epi-2021-0153

Chabanon RM, Morel D, Eychenne T, Colmet-Daage L, Bajrami I, Dorvault N, Garrido M, Meisenberg C, Lamb A, Ngo C, Hopkins SR, Roumeliotis TI, Jouny S, Henon C, Kawai-Kawachi A, Astier C, Konde A, Del Nery E, Massard C, Pettitt SJ, Margueron R, Choudhary JS, Almouzni G, Soria JC, Deutsch E, Downs JA, Lord CJ, Postel-Vinay S. (2021). PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer. Cancer Res. DOI: 10.1158/0008-5472.CAN-21-0628

Pierre Verrelle, Didier Meseure, Frédérique Berger, Audrey Forest, Renaud Leclère, André Nicolas, Emilie Fortas, Xavier Sastre-Garau, Marick Lae, Sabah Boudjemaa, Rodrigue Mbagui, Valentin Calugaru, Dalila Labiod, Leanne De Koning, Geneviève Almouzni and Jean-Pierre Quivy. (2021). CENP-A Subnuclear Localization Pattern as Marker Predicting Curability by Chemoradiation Therapy for Locally Advanced Head and Neck Cancer Patients. Cancers. DOI: 10.3390/cancers13163928

Boumard B, Bardin AJ. An amuse-bouche of stem cell regulation: Underlying principles and mechanisms from adult Drosophila intestinal stem cells. (2021) Curr Opin Cell Biol. Jul 1;73:58-68. DOI: 10.1016/j.ceb.2021.05.007. (invited review)

Riddiford N, Siudeja K, van den Beek M, Boumard B, Bardin AJ. (2021) Evolution and genomic signatures of spontaneous somatic mutation in Drosophila intestinal stem cells. Genome Research 2021 Aug;31(8):1419-1432. DOI: 10.1101/gr.268441.120.

Gervais L, Bardin AJ. Tracheal remodelling supports stem cells. (2021) Nature Cell Biology. 2021 Jun;23(6):580-582. DOI: 10.1038/s41556-021-00695-w.

Siudeja K*#, van den Beek M*, Riddiford N, Boumard B, Wurmser A, Stefanutti M, Bardin AJ#. Unravelling the features of somatic transposition in the Drosophila intestine, EMBO J, May 3;40(9):e106388. DOI: 10.15252/embo.2020106388. *co-first authors, #co-corresponding authors.

F. di Pietro, S. Herszterg, A. Huang, F. Bosveld, C. Alexandre, L. Sancéré, S. Pelletier, A. Joudat, V. Kapoor, J.-P. Vincent, Y. Bellaïche, Rapid and robust optogenetic control of gene expression in Drosophila. Dev. Cell. 56, DOI: 3393-3404.e7 (2021).

S. Park, C. Matte-Martone, D. G. Gonzalez, E. A. Lathrop, D. P. May, C. M. Pineda, J. L. Moore, J. D. Boucher, E. Marsh, A. Schmitter-Sánchez, K. Cockburn, O. Markova, Y. Bellaïche, V. Greco, Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis. Nat. Cell Biol. 23, 476–484 DOI: 10.1038/s41556-021-00670-5 (2021).

Chelmicki T., Roger E., Teissandier A., Dura M., Bonneville L., Rucli S., Dossin F., Fouassier C., Lameiras S. and Bourc’his D. (2021). m6A RNA methylation regulates the fate of endogenous retroviruses. Nature 591, 312-316 doi: 10.1038/s41586-020-03135-1

Barberet J., Binquet C., Guilleman M., Doukani A., Choux C., Bruno C., Bourredjem A., Chapusot C., Bourc’his D., Duffourd D., and Fauque P. (2021). Do assisted reproductive technologies and in vitro embryo culture influence the epigenetic control of imprinted genes and transposable elements in children? Hum Reprod 36, 479-492 doi: 10.1093/humrep/deaa310

Ducreux B., Frappier J., Bruno C., Doukani A., Guilleman M., Simon E., Martinaud A., Bourc'his D., Barberet J. and Fauque P. (2021). Genome-wide analysis of DNA methylation in buccal cells of children conceived through IVF and ICSI. Genes 12, 1912. doi: 10.3390/genes12121912

Klibi J., Joseph C., Delord M., Teissandier A., Lucas B., Chomienne C., Toubert A., Bourc'his D., Guidez F. and Benlagha K. (2021). PLZF acetylation levels regulate NKRT cell differentiation. J Immunol 207, 809-823 doi: 10.4049/jimmunol.2001444

Perez-Palacios R., Fauque P., Teissandier A. and Bourc’his D. (2021). Deciphering the early mouse embryo transcriptome with low-input RNA-seq. Methods Mol Biol 2214, 189-205 doi: 10.1007/978-1-0716-0958-3_13

Dura M., Teissandier A., Armand M., Barau J., Bonneville L., Weber M., Baudrin L.G., Lameiras S. and Bourc’his D. DNMT3A-dependent DNA methylation is required for spermatogonial stem cells to commit to spermatogenesis. (2021). Preprint in bioRxiv doi.org/10.1101/2021.04.19.440465

Glaser J., Iranzo J., Borensztein M., Marinucci M., Gualtieri A., Jouhanneau C., Teissandier A., Gaston Massuet C. and Bourc’his D. The imprinted Zdbf2 gene finely tunes feeding and growth in neonates (2021). Preprint in bioRxiv doi.org/10.1101/2021.01.27.428419

Keizer VIP, Grosse-Holz S, Woringer M, Zambon L, Aizel K, Bongaerts M, Kolar-Znika L, Scolari VF, Hoffmann S, Banigan EJ, Mirny LA, Dahan M, Fachinetti D§ & Coulon A§ (2021). Live-cell micromanipulation of a genomic locus reveals interphase chromatin mechanics. bioRxiv preprint. DOI:10.1101/2021.04.20.439763. § corresponding authors.

Zhang LL, Perez-Romero C, Dostatni N and C Fradin. Using FCS to accurately measure protein concentration in the presence of noise and photobleaching. Biophysical J. 120, 4230-4241, DOI: 10.1016/j.bpj.2021.06.035

Rosin LF, Gil J Jr, Drinnenberg IA, Lei EP. Oligopaint DNA FISH reveals telomere-based meiotic pairing dynamics in the silkworm, Bombyx mori. PLoS Genet. 2021 Jul 28;17(7):e1009700. doi: 10.1371/journal.pgen.1009700. eCollection 2021 Jul. PMID: 34319984

Vanpoperinghe L, Carlier-Grynkorn F, Cornilleau G, Kusakabe T, Drinnenberg IA, Tran PT. Live-cell imaging reveals square shape spindles and long mitosis duration in the silkworm holocentric cells. MicroPubl Biol. 2021 Sep 1;2021:10.17912/micropub.biology.000441. doi:10.17912/micropub.biology.000441. eCollection 2021. PMID: 34514356

Jacquemin* G, Benavente-Diaz M, Djaber S, Bore A, Dangles-Marie V, Surdez D, Tajbakhsh S, Fre* S and Lloyd-Lewis* B. (2021). Longitudinal high-resolution imaging through a flexible intravital imaging window. Science Advances 7 (25), eabg7663DOI: 10.1126/sciadv.abg7663. * co-corresponding authors.

Lloyd-Lewis B, Gobbo F, Perkins M, Jacquemin G, Faraldo M and Fre S. (2021). In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation. bioRxiv preprint, in revision at Cell Reports. DOI: https://doi.org/10.1101/2021.06.22.449401.

Jacquemin G, Wurmser A, Huyghe M, Sun W, Homayed Z, Merle C, Qasrawi F, Perkins M Richon S, Dingli F, Arras G, Loew D, Vignjevic D, Pannequin J and Fre S. (2020). Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme. bioRxiv preprint, in revision at eLife. DOI: https://doi.org/10.1101/2020.12.16.423051.

Schnepf D, Hernandez P, Mahlakõiv T, Crotta S, Sullender ME, Peterson ST, Ohnemus A, Michiels C, Gentle I, Dumoutier L, Reis CA, Diefenbach A, Wack A, Baldridge MT, Staeheli P. Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22. PLoS One. 2021 Aug 12;16(8):e0247738. doi: 10.1371/journal.pone.0247738

Santabárbara-Ruiz P, Léopold P. An Oatp transporter-mediated steroid sink promotes tumor-induced cachexia in Drosophila. Dev Cell. 2021 Oct 11;56(19):2741-2751.e7. doi: 10.1016/j.devcel.2021.09.009. Epub 2021 Oct 4. PMID: 34610327

Arquier N, Bjordal M, Hammann P, Kuhn L, Léopold P. Brain adiponectin signaling controls peripheral insulin response in Drosophila. Nat Commun. 2021 Sep 24;12(1):5633. doi: 10.1038/s41467-021-25940-6. PMID: 34561451; PMCID: PMC8463608

Léopold P. Sizes, proportions and environment. C R Biol. 2021 Jul 2;344(2):165-175. doi: 10.5802/crbiol.48. PMID: 34213854

Boulan L, Léopold P. What determines organ size during development and regeneration? Development. 2021 Jan 11;148(1):dev196063. doi: 10.1242/dev.196063. PMID: 334315

Özgüç, Ö., de Plater, L., Kapoor, V., Tortorelli, A. F. & Maître, J.-L. Zygotic contractility awakening during mouse preimplantation development. http://biorxiv.org/lookup/doi/10.1101/2021.07.09.451745 (2021) doi:10.1101/2021.07.09.451745.

Markus Frederik Schliffka, Anna-Francesca Tortorelli, Özge Özgüç, Ludmilla de Plater, Oliver Polzer, Diane Pelzer, Jean-Léon Maître. Multiscale analysis of single and double maternal-zygotic Myh9 and Myh10 mutants during mouse preimplantation development. eLife 10, e68536 (2021).

Haniffa, M. et al. A roadmap for the Human Developmental Cell Atlas. Nature 597, 196–205 (2021).

Lenne PF, Munro E, Heemskerk I, Warmflash A, Bocanegra-Moreno L, Kishi K, Kicheva A, Long Y, Fruleux A, Boudaoud A, Saunders TE, Caldarelli P, Michaut A, Gros J, Maroudas-Sacks Y, Keren K, Hannezo E, Gartner ZJ, Stormo B, Gladfelter A, Rodrigues A, Shyer A, Minc N, Maître JL, Di Talia S, Khamaisi B, Sprinzak D, Tlili S. Roadmap for the multiscale coupling of biochemical and mechanical signals during development. Phys. Biol. 18, 041501 (2021). Doi: doi: 10.1088/1478-3975/abd0db

Firmin, J. & Maître, J.-L. Morphogenesis of the human preimplantation embryo: bringing mechanics to the clinics. Seminars in Cell & Developmental Biology S1084952121001920 (2021) doi:10.1016/j.semcdb.2021.07.005

Herrera-Delgado, E. & Maître, J.-L. A theoretical understanding of mammalian preimplantation development. Cells & Development 203752 (2021) doi:10.1016/j.cdev.2021.203752

Holoch D, Wassef M, Lövkvist C#, Zielinski D, Aflaki S, Lombard D, Héry T, Loew D, Howard M & R Margueron. A cis-acting mechanism mediates transcriptional memory at Polycomb target genes in mammals. Nat Genet 53, 1686–1697 (2021). https://doi.org/10.1038/s41588-021-00964-2

Chabanon RM, Morel D, Eychenne T, Colmet-Daage L, Bajrami I, Dorvault N, Garrido M, Meisenberg C, Lamb A, Ngo C, Hopkins SR, Roumeliotis TI, Jouny S, Hénon C, Kawai-Kawachi A, Astier C, Konde A, Del Nery E, Massard C, Pettitt SJ, Margueron R, Choudhary JS, Almouzni G, Soria JC, Deutsch E, Downs JA, Lord CJ, Postel-Vinay S. PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer.  Cancer Res. 2021 Apr 22. DOI: 10.1158/0008-5472.CAN-21-0628

Zorro Shahidian L, Haas M, Le Gras S, Nitsch S, Mourão A, Geerlof A, Margueron R, Michaelis J, Daujat S, Schneider R. Succinylation of H3K122 destabilizes nucleosomes and enhances transcription. EMBO Rep. 2021 Jan 29. DOI: 10.15252/embr.202051009

Richart L, Bidard FC, Margueron R. Enhancer rewiring in tumors: an opportunity for therapeutic intervention. Oncogene. 2021 May;40(20):3475-3491. DOI: 10.1038/s41388-021-01793-7

Constanty F, Shkumatava A. lncRNAs in development and differentiation: from sequence motifs to functional characterization. Development. 2021 Jan 13;148(1):dev182741. doi: 10.1242/dev.182741.PMID: 33441380

Loïodice I, Garnier M, Nikolov I, Taddei A. An Inducible System for Silencing Establishment Reveals a Stepwise Mechanism in Which Anchoring at the Nuclear Periphery Precedes Heterochromatin Formation. Cells. 2021 Oct 20;10(11):2810. doi:10.3390/cells10112810

Heltberg ML, Miné-Hattab J, Taddei A, Walczak AM, Mora T. Physical observables to determine the nature of membrane-less cellular sub-compartments. Elife. 2021 Oct 22;10:e69181. doi: 10.7554/eLife.69181

Lautier O., Penzo A., Rouvi.re J.O., Chevreux G., Collet L., Loïodice I., Taddei A., Devaux F., Collart M.A., & B. Palancade. (2021). Co-Translational Assembly and Localized Translation of Nucleoporins in Nuclear Pore Complex Biogenesis. Molecular Cell, S1097276521002252. https://doi.org/10.1016/j.molcel.2021.03.030

Miné-Hattab J. #, Heltberg M., Villemeur M., Guedj C., Mora T., Walczak A.M., Dahan M., & A. Taddei#. (2021) . Single Molecule Microscopy Reveals Key Physical Features of Repair Foci in Living Cells. ELife 10: e60577. https://doi.org/10.7554/eLife.60577. # co-corresponding authors.

Ruault M. *, Scolari V.F. *, Lazar-Stefanita L., Hocher A., Loïodice I., Koszul R. #, & A. Taddei#. (2021) . Sir3 Mediates Long-Range Chromosome Interactions in Budding Yeast. Genome Research 31, no 3: 411-25. https://doi.org/10.1101/gr.267872.120. *Equally contributing authors. # co-corresponding authors